Protein Folding Disorders: From Basic Biology to Public Policy Rodrick Wallace

ISBN: 9781467915946

Published: November 9th 2011

Paperback

138 pages


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Protein Folding Disorders: From Basic Biology to Public Policy  by  Rodrick Wallace

Protein Folding Disorders: From Basic Biology to Public Policy by Rodrick Wallace
November 9th 2011 | Paperback | PDF, EPUB, FB2, DjVu, talking book, mp3, ZIP | 138 pages | ISBN: 9781467915946 | 7.29 Mb

Protein folding dysfunctions like Alzheimers and Parkinsons Diseases present intractable medical challenges: drug treatments are, at best, palliative, failing to alter ultimate disease course. Effective intervention will require a deeperMoreProtein folding dysfunctions like Alzheimers and Parkinsons Diseases present intractable medical challenges: drug treatments are, at best, palliative, failing to alter ultimate disease course.

Effective intervention will require a deeper understanding of protein folding and its regulation, particularly in view of a sixfold rise in the inflation-adjusted cost of bringing drugs to market since 1950. As a consequence, the pharmaceutical industry has sharply curtailed research on a range of poorly-understood afflictions, including Alzheimers Disease. That is, in all likelihood, there will not be effective drugs for many protein folding disorders anytime soon, and, if produced, the costs will be prohibitive.

Here we follow protein folding and its failure from the cellular to social levels of organization, finding a strong foundation for effective public health interventions against the early onset of disease.



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